Could exfoliation syndrome be a systemic disease, rather than only an ocular disease?
a) It can be since exfoliation material is not restricted to intraocular tissues
b) It can not be because exfoliation material is produced only by the lens and iris
a) It can be since exfoliation material is not restricted to intraocular tissues (this statement is correct, exfoliation material is found on ocular tissues, such as: conj, orbital tissue, extraocular muscles, optic nerve, and ciliary arteries. It is also found systemically in skin, lungs, heart muscle, vessel walls, liver, kidney, gall bladder, and cerebral meninges)– *in conclusion, XFS is a systemic disease but the role of exfoliation material in causing or exaggerating the systemic diseases remains to be clarified