Pharmacology: Drug Absorption and Distribution

Absorption describes the transfer of drug from the site of administration to the general circulation

The aim of drug therapy is to
rapidly deliver & maintain therapeutic, yet nontoxic levels of drug in the target tissues.

the speed of onset of drug action, the intensity of the drugĀ“s effect & the duration of the drug action are controlled by 3 fundamental pathways of drug movement in the body:
1. drug absorption from the site of administration.
2. drug leaving the blood stream & its distribution into the interstitial & intracellular fluids (distribution)
3. hepatic metabolism & urinary excretion of the drug & its metabolites.